19F-TP-LNE Diameter (nm) Zeta potential (mV) Small-LNE 58 ±3 -34 ±3 Large-LNE 157 ±4 -53 ±9 PEG-LNE 174 ±4 -32 ±2

Table 2: Particle size and zeta potential of 19F-TP-LNEs (n=3).