| Variables |
Pre-transplant
N=49 (100%) |
Deceased for complications
N=9/49 (18.4%) |
Tu. relapse<36 mts.
N=6/40 (15%) |
Tu. relapse>36 mts.
N=5/40 (12.5%) |
HCC free>54 mts.
N=29/40 (72.5%) |
| Demographic & clinic-pathologic features |
|
|
|
| Median age |
58 |
57 |
56 |
48 |
47 |
| Female |
17 (34.6%) |
4 (44.4%) |
1 (16.6%) |
3 (60.0%) |
9 (31.0%) |
| Male |
32 (65.4%) |
5 (55.6%) |
5 (83.4%) |
2 (40.0%) |
20 (69.0%) |
| HCV incl. ALD |
38 (77.5%)
(12 with ALD) |
6 (66.6%)
(4 with ALD) |
6 (100%)
(4 with ALD) |
4 (80.0%)
(1 with ALD) |
26 (76.5%)
(3 with ALD) |
| HBV |
11 (22.5%) |
3 (33.4%) |
none |
1 (20.0%) |
7 (24.1%) |
| Child-Pugh A |
35 (71.4%) |
3 (33.4%) |
3 (50%) |
4 (80.0%) |
25 (86.2%) |
| Child-Pugh B |
14 (28.6%) |
6 (66.6%) |
3 (50%) |
1 (20.0%) |
4 (13.8%) |
| Serum AFP level (ng/mL) |
1233 (± 3292)
43.7 (287-2178 95%CI) |
92.4 (± 82.54)
144.4(28.95 -155.84 95% CI) |
9470 (± 4446)
6869 (562-10490 95% CI) |
2541.2 (± 5506)
114.4 (-4295-9378 95% CI) |
473.6 (± 2231)
25.5 (-375.2-1322 95% CI) |
| Platelets count
(×103/mcL) |
83.4 (± 42.8)
75.0 (71.1-95.7 95% CI) |
54.5 (± 23.08)
38.0 (36.8-72.3
95% CI) |
74.0 (± 14.58)
76.5 (58.6-89.31
95% CI) |
96.4 (± 78,4)
61.0 (-5.0-193.3
95% CI) |
92.0 (SD ± 41)
78.0 (76.0-107.0 95% CI) |
| Tumor characteristic |
|
|
|
|
| Solitary < 5 cm. |
27 (55.1%) |
5 (55.6%) |
none |
3 (60.0%) |
19 (65.5%) |
| Multifocal |
22 (44.9%) |
4 (44.4%) |
6 (100%) |
2 (40.0%) |
10 (34.5%) |
| Good different. |
10 (20.4%) |
3 (33.4%) |
4 (66.6%) |
none |
3 (10.4 %) |
| Moderate differ. |
31 (63.3%) |
5 (55.6%) |
2 (33.4%) |
2 (40.0%) |
22 (75.8%) |
| Poor different. |
8 (16.3%) |
1 (11%) |
none |
3 (60.0%) |
4 (13.8%) |
| Microvascular invasion present |
11 (22.4%) |
1 (11%) |
4 (66.6%) |
3 (60.0%) |
3 (10.3%) |
| Soluble angiogenesis factors |
|
|
|
|
| %HSCs/WBC |
0.015 (± 0.008)
0.0148 (0.012-0.017 95% CI) |
0.014 (±0.005)
0.015 (0.0104-
0.0182 95% CI) |
0.029 (± 0.005)
0.030 (0.0244-0.03 95% CI) |
0.019 (± 0.006)
0.015 (0.01-0.026 95% CI) |
0.011 (± 0.006)
0.0117 (0.01-0.018 95% CI) |
| %EPCs/HSCs |
3.468 (± 1.08)
3.410 (3.156-3.779 95% CI) |
3.249 (±0.72)
2.985 (2.695-3.80 95% CI) |
5.054 (± 1.08)
5.169 (3.916-6.19 95% CI) |
4.235 (± 0.79)
4.301 (3.25-5.221 95% CI) |
3.075 (± 0.86)
3.149 (2.747-3.404 95% CI) |
| VEGF level (pg/mL) |
317.4 (± 241.9)
317.7 (247.9-386.9 95% CI) |
423.1 (± 245.3)
411.3 (234.55-611.68 95% CI) |
313.9 (± 161.2)
331.5 (144.74-483.24 95% CI) |
298.3 (± 153.1)
345.23 (108.13-488.5 95% CI) |
288.6 (± 265.8)
261.98 (187.57-389.81 95% CI) |
Values are presented as N (%), mean & median 95% CI.