Authors Target Assay methods Function Result References
Nishio et al. human dental plaque SEM1 plaque formation less plaque formation 22
  S. oralis SEM, labeled bacterial count adherence no difference  
Honda et al. human dental plaque SEM plaque formation less plaque formation 23
  huma saliva EDS film-like interface substance anti-bacterial layer formation  
Hirose et al. Streptococci SEM adherence less S. sanguinisadherence 27
  albumin 125I-labeled albumin albumin adsorption more albumin adsorption  
Tamoto et al. human dental plaque SEM plaque formation less plaque formation 24
    EDS film-like interface substance Al, Si, and Sr were detected from the thin layer  
Han et al. P. acnes, A. israelii, E. faecalis agar difusion method antibacterial test anti-bacterial effect on P. acnes, A. israelii 37
Daneshmehr et al. S. mutans SEM biofilm formation less biofilm formation 28
Yoshida et al. human dental plaque SEM plaque formation less plaque formation 25
  S. sanguinis, S. salivarius, S. oralis 3H-labeled bacterial count adherence no difference  
Idono et al. human dental plaque SEM plaque formation less plaque formation 26
  S. oralis SEM adherence less adherence  
  S. oralis colony count antibacterial test no difference  
Saku et al. S. mutans SEM, 3H-labeled bacterial count adherence less adherence 29
  S. mutans colony count antibacterial test no difference  
Tamura et al. S. sanguie and S. oralis growth curve examination growth inhibition growth inhibition 34
Kimyai et al. S. mutans SEM, bacterial count adherence less adherence 30
Ma et al. S. mutans pH electrode pH change less pH decrease 33
  S. mutans micro-CT scanning, SEM demineralization less demineralization  
Yoneda et al. S. mutans safranin-based micoplate assay adherence less adherence 38
  P. gingivalis BAPNA2, gelatin film assay enzyme activities less enzyme activities  
  P. gingivalisand F. nucleatum coaggregation assay coaggregation less coaggregation  
Hotta et al. S. mutans SEM, labeled bacterial count adherence less adherence 31
  S. sanguinis SEM, 3H-labeled bacterial count adherence no difference  
Kuramochi et al. huma saliva bacterial count of PM biofilm3 biofilm formation less biofilm formation 35
Hahnel et al. S. mutans MTT-based microplate assay biofilm formation less biofilm formation 32
Suzuki et al. huma saliva colony count antibacterial test less viable bacteria 36
  huma saliva safranin-based micoplate assay biofilm formation and disruption less biofilm formation and biofilm disuruptive effect  
  oral molodor halimeter assay VSCs4produciton less VSCs production  
1scanning electron microscopy
2Na-benzoyl-L-arginine 4-nitroanilide hydrochloride
3polymicrobial biofilm
4volatile sulfur compounds
Table 2: Antibacterial effect of S-PRG.