Formulation Active ingredient Label claim (mg) Amount found (mg) A.M ± SDa %Assay % RSDb Flexura- 400 MET 400 396.2+0.097 99.05 0.024 Pradaxa-110mg DAB 110 111 ± 0.11 100.9 0.099 aMean of three determinations bRelative standard deviation (%)

Table 4: Assay of MET and DAB using MBTH.