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Figure 5: Evaluation of glomerular endothelial surface layer integrity following chronic drug monotherapy or combination therapy. (A) WGA staining. Scale bar=50 μm. (B) WGA staining score. N>80 tissue samples for each treatment group. *p<0.05 vs. Cont. †p<0.05 vs. DM. (C) Relative heparanase mRNA expression in isolated glomeruli. *p<0.05 vs. Cont. †p< 0.05 vs. DM.