Table 2

	Cont	DM	Amlo	Cilni	Irbe + Amlo	Irbe + Cilni
Number	7	7	7	7	7	7
SBP	123 ± 2	126 ± 2	113 ± 3^a,b	111 ± 3^a,b	98 ±3^a,b,c	99 ±4^a,b,d
BW	543 ± 20	382 ± 13^a	378±13^a	381±24^a	401 ±18^a	408 ± 23^a
Serum glucose	143 ± 10	623 ± 31^a	633 ± 21^a	611± 45^a	594 ± 29^a	664 ± 55^a
Serum Cre	0.21 ± 0.01	0.16 ± 0.01^a	0.17 ± 0.01^a	0.17 ± 0.01^a	0.16 ± 0.01^a	0.17 ± 0.02^a
BUN	21.6 ± 0.8	27.0 ± 2.4^a	26.8± 1.2^a	28.2 ± 1.5^a	25.6 ± 1.4^a	28.4 ± 2.4^a

Data are expressed as mean ± SEM. ^aP<0.05 vs. Cont. ^bP<0.05 vs. DM. ^cP<0.05 vs. Amlo. ^dP<0.05 vs. Cilni.
SBP: systolic blood pressure (mmHg); BW: body weight (g); Cre: Creatinine (mg/dL); BUN: blood urea nitrogen (mg/dL); Cont: non diabetic control; DM: streptozotocininduced diabetes; Amlo: amlodipine; Cilni: cilnidipine; Irbe: irbesartan.

Table 2: Physiological and biochemical changes following chronic treatment.