Excipients |
Amount added (mg) |
Azithromycina
% Recovery ± SD |
Cephalexin monohydrateb
% Recovery ± SD |
Lactose |
20 |
99.3 ± 0.7 |
98.2 ± 0.3 |
Dextrose |
20 |
98.4 ± 0.9 |
99.5 ± 0.7 |
Cellulose |
20 |
98.5 ± 0.8 |
101.1 ± 0.6 |
Magnesium stearate |
20 |
101.2 ± 0.4 |
99.4 ± 0.4 |
Talc |
20 |
98.4 ± 0.4 |
100.2 ± 0.4 |
Starch |
20 |
99.5 ± 0.2 |
99.4 ± 0.7 |
Gelatine |
20 |
100.2 ± 0.5 |
98.8 ± 0.6 |
|
a40 (μg m L-1) of azithromycin
b100 (μg m L-1) of cephalexin monohydrate |
Table 5: Determination of drugs in presence of excipients. |