| Parameters |
Mean |
SD |
| Cmax (μg/mL) |
28.07 |
7.52 |
| t1/2α (min) |
0.55 |
0.17 |
| t1/2β (min) |
3.33 |
0.69 |
| t1/2γ (min) |
26.57 |
24.10 |
| V1 (l/kg) |
0.083 |
0.046 |
| CL (L/min/kg) |
0.041 |
0.009 |
| AUC(0-60)（mg·min/L） |
115.10 |
20.49 |
| AUC(0-∞)（mg·min/L） |
121.36 |
25.70 |
|
| Cmax: the maximum plasma concentration; t1/2α: Half-life of rapid distribution
phase; t1/2β: half-life of slow distribution phase; t1/2γ: half-life of elimination phase;
V1: apparent volumes of distribution of the central compartments; CL: total body
clearance; AUC: area under the plasma concentration vs. time curve. |
| Table 4: Pharmacokinetic parameters of STS followed after a single intravenous
administration of STS at a dose of 6 mg/kg (n = 6). |