Assay PPCP Effect   5 µg/mL 25 µg/mL 125 µg/mL MDAb β-Estradiol + + ++ Gemfibrozil + + + Catalasec       β-Estradiol + + + Gemfibrozil + + + Electrolyte Leakaged β-Estradiol + + + Gemfibrozil + + ++ Chlorophylle β-Estradiol NC NC NC Gemfibrozil NC NC NC

aData from Osma et al. (unpublished). bMalondialdehyde (MDA) is an end product of lipid peroxidation. cProtects plant cells from oxidative damage by reactive oxygen species. dA general indicator of plant stress. eTotal of Chlorophyll A + Chlorophyll B. +: increase in parameter relative to control ++: 2X increase in parameter relative to control NC = no change relative to control

Table 2: Example data from plant (wheat, Triticum aestivum) stress biomarker responses (relative to controls) to PPCP exposurea.