| Case No |
Age |
Body Height (cm) |
Body Weight (Kg) |
Para |
Bishop Score* |
Concentation of misoprostol acid (fg/μL) |
Dosing Regimen |
| Time 0 |
Time 1 |
Time 2 |
| 1 |
24.0 |
159 |
74.0 |
3 |
5 |
N.D. |
N.D. |
N.D. |
20μg→20μg→20μg |
| 2 |
25.9 |
158 |
78.0 |
1 |
3 |
N.D. |
N.D. |
N.D. |
20μg→20μg→20μg→20μg→20μg |
| 3 |
30.7 |
158 |
60.0 |
2 |
4 |
N.D. |
N.D. |
N.D. |
20μg→20μg→20μg→20μg→40μg→40μg→20μg |
| 4 |
32.5 |
18 |
70.0 |
4 |
8 |
N.D. |
7.7 |
8.8 |
20μg→20μg→20μg→20μg→40μg→40μg→40μg |
| 5 |
24.8 |
165 |
67.0 |
3 |
4 |
N.D. |
4.7 |
N.D. |
20μg→20μg→20μg→20μg→40μg→40μg→40μg |
| |
|
|
|
|
|
|
|
|
→40μg→60μg→40μg→40μg |
|
| *: Bishop score on admission before labor induction or augmentation |
| N.D.: Non-Detectable |
| Time 0: Immediately after initial misoprostol administration. |
| Time 1: At the start of regular uterine contractions. |
| Time 2: At full cervical dilatation. |
| Table 2: Pharmacokinetic analysis of five regimens of hourly oral misoprostol administration. |
