Parameters 50mg/kgbw 100mg/kgbw
Day 0 Day 7 Day 14 Day 0 Day 7 Day 14
WBC (x103/μL) 6.10 ± 0.53a 8.28 ± 0.89ab 10.78 ± 0.35b 5.56 ± 0.32a 6.78 ± 0.48a 10.70 ± 0.51b
Neutrophils (%) 1.14 ± 0.15a 1.62 ± 0.11ab 2.24 ± 0.22b 1.24 ± 0.23a 1.50 ± 0.28a 1.90 ± 0.38a
Lymphocytes (%) 4.58 ± 0.38a 4.28 ± 0.28a 3.94 ± 0.22a 3.98 ± 0.17a 3.98 ± 0.12a 4.40 ± 0.45a
Monocytes (%) 0.02 ± 0.02a 0.26 ± 0.06a 0.12 ± 0.07a 0.02 ± 0.02a 0.28 ± 0.11a 0.34 ± 0.05a
Eosinophils(%) 0.00 ± 0.00a 0.04 ± 0.04a 0.12 ± 0.04a 0.06 ± 0.04a 0.00 ± 0.00a 0.04 ± 0.02a
Basophils (%) 0.56 ± 0.07a 3.00 ± 0.05b 4.32 ± 0.19c 0.34 ± 0.07a 2.22 ± 0.21b 2.90 ± 0.37b
All values are expressed as mean ± SEM for five animals per group. Values for each parameter are compared among day 0, 7 and 14 for each dose by ANOVA and Tukey’s post hoc test.
Table 2: Effects of methanolic seed extract of S. incanum (Linn) on white blood cells and their differentials parameter profiles in normal mice.