Stationary Phase Mobile Phase Detection Linearity; LOD/LOQ Application Reference
C18 Methanol-0.04M ammonium acetate-acetonitrile (38:38:24v/v/v) +0.02% TEA (final pH 7.1) UV at 240 nm 2.5-100 ng/ml Pharmacokinetic studies in rats 28
C18 Acetonitrile-methanol-pH 3.0, triethylamine solution (15:35:50 v/v/v) UV at 237 nm 0.39-1.56 μg/ml;
LOD: 0.02 μg/ml
LOQ: 0.08 μg/ml
Detection of amlodipine besylate residues in swab samples 29
C18 (A) 0.04M Ammonium acetate-methanol-acetonitrile (30:30:40v/v/v); (B) 1% acetic acid-methanol (1:1 v/v) (A) UV at 240nm;
(B) MS at 2 kV soft ionization with positive mode
C18 1% Triethylamine (pH3.0)-acetonitrile (65:35 v/v) UV at 220nm 75-180 ppm
LOQ:21-35 ppm
Quantification of alkyl benzene sulfonates in amlodipine besylate 31
C18 Acetonitrile and 0.05M sodium dihydrogen phosphate buffer
(60:40)pH 6
UV at 254 nm amlodipine besylate:
5-30 μg/ml and telmisartan:
10-60 μg/ml
Pharmaceutical dosage form 32
C18 0.02M Potassium dihydrogen orthophosphate: acetonitrile (30:70 v/v)pH5 UV at 245 nm Telmisartan:
32-96μg/ml Amlodipin:
Tablet dosage form 33
C18 Buffer (0.7 % aqueous triethylamine pH 3 and methanol in the ratio of 40:60 (v/v) UV at 239 nm 20-150 μg/ml Pharmaceutical dosage form(Oral Film) Present Research
Table 1: Comparison of the performance characteristics of the present research method with the published methods.