|
TREATMENT |
BLOOD GLUCOSE LEVELS AT VARYING TIMES (mmoles/L) |
| 0hr |
1hr |
2hr |
3hr |
4hr |
7hr |
24hr |
| Control/Saline |
5.20 ± 0.07c |
5.34 ± 0.11e |
5.32 ± 0.08d |
5.22 ± 0.08b |
5.16 ± 0.05 b |
5.22 ± 0.08 b |
5.24 ± 0.15c |
| Diabetic/Saline |
14.52 ± 2.97ba |
16.02 ± 2.48a |
17.52 ± 2.62a |
19.20 ± 2.88a |
21.22 ± 3.23a |
22.50 ± 3.48a |
25.00 ± 2.98a |
| Diabetic/insulin |
17.46 ± 2.99a |
8.62 ± 0.55edc |
6.20 ± 0.56cd |
9.32 ± 0.29 b |
4.96 ± 0.11 b |
4.70 ± 0.28 b |
6.30 ± 0.79cb |
| 25(mg/kgbw) |
15.42 ± 1.26ba |
12.68 ± 3.11bac |
8.90 ± 1.64cb |
6.80 ± 1.06 b |
5.44 ± 0.78 b |
4.68 ± 0.48 b |
6.64 ± 1.15cb |
| 48.4(mg/kgbw) |
16.48 ± 2.91ba |
14.98 ± 3.49ba |
10.46 ± 2.36b |
7.60 ± 1.25 b |
6.24 ± 1.23 b |
5.18 ± 0.74 b |
8.48 ± 1.44 b |
| 93.5(mg/kgbw) |
13.68 ± 2.55ba |
7.48 ± 0.91ed |
6.30 ± 0.46cd |
5.54 ± 0.43 b |
5.90 ± 0.72 b |
4.62 ± 0.36 b |
8.12 ± 1.54cb |
| 180.9(mg/kgbw) |
12.50 ± 1.02b |
9.42 ± 1.04adc |
7.28 ± 0.98cbd |
6.16 ± 0.23 b |
5.48 ± 0.34 b |
5.02 ± 0.15 b |
7.84 ± 0.59cb |
| 350(mg/kgbw) |
15.96 ± 3.33ba |
11.36 ± 2.76bdc |
8.88 ± 2.08cb |
6.94 ± 1.30 b |
5.68 ± 0.98 b |
5.14 ± 0.70 b |
6.64 ± 0.55cb |
|
| Results are expressed as Means ± SD for five mice per group. Values followed by
the same superscript are not statistically different (P ≤ 0.05; analysed by ANOVA
followed by Tukey’s post hoc test. |
| Table 1: Effects of intraperitoneally administered aqueous leaf extracts of Croton
macrostachyus on blood glucose levels in alloxan induced diabetic mice |
