TREATMENT BLOOD GLUCOSE LEVELS AT VARYING TIMES (mmoles/L)
0hr 1hr 2hr 3hr 4hr 7hr 24hr
Control/Saline 5.20 ± 0.07c 5.34 ± 0.11e 5.32 ± 0.08d 5.22 ± 0.08b 5.16 ± 0.05 b 5.22 ± 0.08 b 5.24 ± 0.15c
Diabetic/Saline 14.52 ± 2.97ba 16.02 ± 2.48a 17.52 ± 2.62a 19.20 ± 2.88a 21.22 ± 3.23a 22.50 ± 3.48a 25.00 ± 2.98a
Diabetic/insulin 17.46 ± 2.99a 8.62 ± 0.55edc 6.20 ± 0.56cd 9.32 ± 0.29 b 4.96 ± 0.11 b 4.70 ± 0.28 b 6.30 ± 0.79cb
25(mg/kgbw) 15.42 ± 1.26ba 12.68 ± 3.11bac 8.90 ± 1.64cb 6.80 ± 1.06 b 5.44 ± 0.78 b 4.68 ± 0.48 b 6.64 ± 1.15cb
48.4(mg/kgbw) 16.48 ± 2.91ba 14.98 ± 3.49ba 10.46 ± 2.36b 7.60 ± 1.25 b 6.24 ± 1.23 b 5.18 ± 0.74 b 8.48 ± 1.44 b
93.5(mg/kgbw) 13.68 ± 2.55ba 7.48 ± 0.91ed 6.30 ± 0.46cd 5.54 ± 0.43 b 5.90 ± 0.72 b 4.62 ± 0.36 b 8.12 ± 1.54cb
180.9(mg/kgbw) 12.50 ± 1.02b 9.42 ± 1.04adc 7.28 ± 0.98cbd 6.16 ± 0.23 b 5.48 ± 0.34 b 5.02 ± 0.15 b 7.84 ± 0.59cb
350(mg/kgbw) 15.96 ± 3.33ba 11.36 ± 2.76bdc 8.88 ± 2.08cb 6.94 ± 1.30 b 5.68 ± 0.98 b 5.14 ± 0.70 b 6.64 ± 0.55cb
Results are expressed as Means ± SD for five mice per group. Values followed by the same superscript are not statistically different (P ≤ 0.05; analysed by ANOVA followed by Tukey’s post hoc test.
Table 1: Effects of intraperitoneally administered aqueous leaf extracts of Croton macrostachyus on blood glucose levels in alloxan induced diabetic mice