Animal Groups (N=5) |
Treatment |
Phase1 |
Phase2 |
Baseline |
Formalin (2.5%) |
258.60±10.9a
(2.78) |
803.80±1.74a (11.88) |
Negative Control |
DMSO (30%) |
266.00±8.14a
(0.00) |
718.40±2.66a
(0.00) |
Positive Control |
Diclofenac (15mg/kgbw) |
259.40±3.44a
(2.63) |
14.20±1.20b
(98.02) |
Acetone Extract |
50mg/kgbw |
227.20±3.89a
(14.59) |
195.80±2.60b
(72.74) |
|
100mg/kgbw |
226.80±4.28a
(14.73) |
4.00±0.71ac
(99.38) |
|
Values are expressed as Mean ± SEM for five animals per group. Values with the same superscript are not significantly different by ANOVA followed by Tukey’s post hoc test (p˃ 0.05). The figures in blankets represent % inhibition. |
Table 1: Antinociceptive activities of acetone leaf extracts of C. volkensii on formalin induced pain in mice. |