Figure 8: Dose responses of rat brain major endocannabinoids (AEA, 2-AG, 2-OG, 2-PG and 2-LG) in rats treated with various oral single doses of JNJ4218734 at 0, 0.3, 1, 3, 10 and 30 mg/kg. The data represents a mean ± SEM, n = 8 per group.