| Physical parametersformulations |
Weight variation (%) |
Friability(%) |
Hardness(N) |
Diameter(mm) |
Thickness (mm) |
| C* |
C |
C* |
C |
C* |
C |
C* |
C |
C* |
C |
| F1 |
0.018 |
0.038 |
0.09±.034 |
0 |
21.08±0.305 |
21.18±0.469 |
12.032±0.006 |
12.140±0.01 |
4.049±0.007 |
4.159±0.009 |
| F2 |
0.02 |
0.026 |
0.117±0.062 |
0 |
21.10±0.261 |
21.22±0.828 |
12.045±0.005 |
12.183±0.01 |
4.046±0.005 |
4.218±0.010 |
| F3 |
0.021 |
0.035 |
0.143±0.071 |
0 |
20.38±0.286 |
20.59±0.536 |
12.041±0.005 |
12.244±0.012 |
4.052±0.006 |
4.321±0.012 |
| F4 |
0.084 |
0.026 |
0.042 ± 0.091 |
0 |
20.19 ± 0.176 |
20.49
± 0.260 |
12.038 ± 0.005 |
12.389 ± 0.012 |
4.054 ± 0.005 |
4.345 ± 0.005 |
| F5 |
0.027 |
0.097 |
0.125 ± 0.101 |
0 |
21.03 ± 0.433 |
21.36 ± 0.743 |
12.045 ± 0.006 |
12.311 ± 0.018 |
4.048 ± 0.004 |
4.358 ± 0.008 |
| F6 |
0.023 |
0.117 |
0.126 ± 0.098 |
0 |
20.53 ± 0.419 |
20.9 ± 0.510 |
12.041 ± 0.005 |
12.440 ± 0.008 |
4.05 ± 0.008 |
4.358 ± 0.009 |
| F7 |
0.023 |
0.023 |
0.165 ± 0.102 |
0 |
21.14 ± 0.508 |
21.35 ± 0.638 |
12.041 ± 0.005 |
12.622 ± 0.016 |
4.043 ± 0.008 |
4.371 ± 0.007 |
| F8 |
0.02 |
0.078 |
0.132 ± 0.094 |
0 |
21.28 ± 0.192 |
21.55 ± 0.331 |
12.047 ± 0.004 |
12.678 ± 0.01 |
4.056 ± 0.007 |
4.382 ± 0.006 |
| F9 |
0.021 |
0.188 |
0.068 ± 0.18 |
0 |
21.09 ± 0.428 |
21.47 ± 0.802 |
12.047 ± 0.004 |
12.629 ± 0.019 |
4.058 ± 0.006 |
4.633 ± 0.011 |
|
# Value with “±” showed standard deviation
C*, Uncoated tablet; C, Coated tablet |
| Table 3: Effect of Eudragit™ L100 coating on physical parameters of prepared tablets#. |
