Drug Label claim % Founda ± SD
Proposed methods Official method
BPB BCP Conductometry
Allergy stop 60 mg/cap 100.80 ± 0.19
t =1.99
F =2.14
101.20 ± 0.21
t =2.17
F
=2.61
101.04 ± 0.17
t =1.91
F =1.71
100.79 ± 0.13
t
=1.32
  120 mg/tab 101.40 ± 0.20
t =2.05
F
=1.78
100.80 ± 0.18
t =1.75
F =1.44
100.01 ± 0.19
t =2.01
F
=1.60
101.05 ± 0.15
t =1.28
  180 mg/tab 99.88 ± 0.18
t =1.68
F =1.65
100.60 ± 0.20
t =1.36
F
=2.04
99.91 ± 0.16
t =1.73
F =1.31
99.78 ± 0.14
t =1.79
Fexodine 60 mg/cap 99.76 ± 0.16
t =2.20
F
=1.00
99.85 ± 0.19
t =1.67
F =1.41
100.95 ± 0.21
t =1.82
F =1.72
99.71 ± 0.16
t =1.24
Fenadin 120 mg/tab 101.32 ± 0.22
t =1.91
F =1.67
102.15 ± 0.21
t =1.31
F =1.52
100.22 ± 0.14
t =1.07
F =1.47
99.69 ± 0.17
t =1.23
  180 mg/tab 100.95 ± 0.20
t =1.70
F
=1.23
101.08 ± 0.23
t =1.12
F
=1.63
100.30 ± 0.32
t =2.09
F =3.16
100.52 ± 0.18
t =1.81
aFive independent analyses. At 95% confidence level t-value is 2.776 and F-value is 6.26
Table 4: Determination of FEX in different pharmaceutical formulations by the proposed and official methods.