Concentration (µM) nmol of MDA (TBARS) Diphenyl Diselnide  (DPDS) Basal (B) 218±16 SNP­­ –Induceda* 351±31* SNP ­­ + 4μMa 334±30 SNP ­­ + 10μMb 196±12 SNP + 40μMb 154±19 SNP + 100μMb 67±21 Diphenyl Ditelluride (DPDT) Basal (B) 274 ±21 SNP­­ –Induceda* 536 ±34* SNP + 1 μMa 503 ±25 SNP + 1.2 μMb 341 ±19 SNP + 1.4 μMc 213 ±17 SNP + 1.6 μMe 44 ±7

Table2: Effect of Diphenyl Diselenide (DPDS) and Diphenyl Ditelluride (DPDT) on TBARS production in rat’s brain preparation. TBARS are expressed as nmol of MDA/g of tissue. Data are presented as mean ± S.E.M. (n = 5). Asterisk presents the significant effect of SNP while different letters represent significant effect of the tested compounds.