Figure 3: Structural alignment of cyclophilins. A- Structural alignment of apo cyclophilin from M. perniciosa (blue – 3O7T), M. sympodialis (magenta – 2CFE), human (yellow – 1OCA) and S. cerevisiae (pink – 1IST). B- Structural alignment of apo (blue – 3O7T) and bound (gray – 3PMP) forms from M. perniciosa. IN- terminus; II- Loop localized between β-strand 4 and β-strand 5; III- Loop localized between α-helix 2 and β-strand 8.