Figure 1: Total locomotor activities after acute saline or cocaine administration. Data are presented as either (A) the sum of activity or (B) mean ± SEM activity during 5 minute time block intervals. Saline-treated males are represented by open squares saline-treated females by open diamonds cocaine-treated males by solid squares, and cocaine-treated females by solid diamonds. N = 7-8 per group. * Represents statistically significant differences between male and female groups. ^ Represents a Drug X Sex X Time significant interaction (p < 0.05).