phospho
Figure 2: Time course of changes in phospho-(Ser/Thr)-PKA substrate protein levels in the NAcc after cocaine administration in male and female rats. P-(Ser/Thr)-PKA substrate protein levels are expressed as mean ± SEM values, normalized to α-tubulin levels. The basal level of p-(Ser/Thr)-PKA substrate protein levels in both male and female rats (A). Zero to 90 minutes after acute cocaine administration in (B) male and (C) female rats. Representative immunoblots of PKA and α-tubulin were indicated in lower panels.
* Represents significant differences to saline-treated controls; p < 0.05. White bars represent levels of saline-treated groups. Shaded bars represent levels of cocainetreated groups. N = 4 per group.