| |
Drugs |
Adverse effects |
| 1 |
SSRIs (Prozac, Paxil, Zoloft) |
Increased GI activity, anorgasmia, akathisia, apathy, anxiety, and when toxic, a serotonin syndrome. |
| 2 |
Bupropion (Wellbutrin) |
Contraindicated in patients with unstable seizure disorder; multiple divided dosing. |
| 3 |
Venlafaxine (Effexor) |
Initial stimulant side effects may disturb some patients, may increase blood pressure in hypertensive; GI side effects (also common with antiretrovirals) |
| 4 |
Trazodone (Desyrel) |
May cause sedation in a.m. at 50-100 mg when taken at night; 1/7000 incidence of priapism. |
| 5 |
Tricyclics |
Weight gain, constipation, orthostatic hypotension, dry mouth, sedation. Can be lethal in overdose. |
| 6 |
Hormones (testosterone, DHEA) |
Off-label for treating depression, side effects with hormone treatment impact biological functions. |
| Source: HIV mental health treatment issues. |
