Group Cortisol/DHEA DHEA/DHEA-S Volunteers prior to therapy 14.52 13.38 Volunteers after treatment 13.95 13.41 Patients prior to therapy 28.07* 11.34* Patients after treatment 18.53* 21.07*

Table 2: The ratio cortisol/DHEA and DHEA/DHEA-S in alcoholic patients and healthy volunteers before and after treatment, *: The level of significant difference P < 0.005.