Alcoholcue Smoking cue Cannabis cue Cross-SPU Subsamplealcohol/ tobacco N = 2,540 No. of symptoms of alcohol dependence Non/occasional SPU -3.58 -5.18*** - -10.10*** Alcoholcue - -2.2 - -7.99*** Smoking cue  - -  -  -4.49** No. of symptoms of nicotine dependence Non/occasional SPU -16.63*** 3.17 - -11.23*** Alcoholcue - 22.11*** - 9.20*** Smoking cue  - -  -  -16.95*** Subsamplealcohol/ cannabis N = 1,730 No. of symptoms of alcohol dependence Non/occasional SPU 0.48 - -4.84*** -6.87*** Alcoholcue - - -4.09* -5.92*** Cannabis cue  - - -   -2.85 No. of symptoms of problematic cannabis use Non/occasional SPU -29.84*** - 2.38 -28.73*** Alcoholcue - - 32.00*** 4.36** Cannabis cue -  -  -  -31.26*** Subsampletobacco/ cannabis N = 1,429 No. of symptoms of nicotine dependence Non/occasional SPU - -0.92 -8.55*** -12.63*** Smoking cue - - -3.90** -6.63*** Cannabis cue -  - -   -5.12*** No. of symptoms of problematic cannabis use Non/occasional SPU - -14.44*** -3.92 -28.04*** Smoking cue - - 12.60*** -2.36 Cannabis cue -  - -   -26.26***

Table 4: Post-hoc comparisons of ANOVA for the number of symptoms of alcohol, tobacco and cannabis dependence according to groups of simultaneous user’s t-tests with corrected p-value are given (Bonferroni corrections). Example: post-hoc comparison of non/occasional SPU users versus complete SPU users for the number of symptoms of alcohol dependence: t = -3.58. Means are given in Table 3. Adjusted results for hazardous use of alcohol, tobacco and cannabis are given. ***p < .001; **p < .01; *p < .05.