Lumbar Spine T-score Femoral  neck  T-score
HIV mono-infected  n = 129 HIV/HCV co-infected n = 65 HIV mono-infected  n = 129 HIV/HCV co-infected n = 65
  Analysis Analysis Analysis  
Univariate Multivariate Univariate Multivariate Univariate Multivariate Univariate Multivariate
Demographic/lifestyle characteristics   P< β P<   P< β P<   P< β P<   P< β P<
      Age -0.24* 0.01 - - -0.16 ns - - -0.22 0.01 - - -0.18* ns - -
      BMI (kg/m2) 0.17* Ns - - 0.15* ns - - 0.25* 0.01 - - 0.27* 0.04 0.36 0.03
      Menopause -0.04° ns - - -0.3° 0.02 - - -0.03° ns - - -0.27° 0.04 - -
Biochemical parameters
Bone alkaline phosphatase  (IU/L) -0.3* 0.01 - - -0.26* 0.05 - - -0.28* 0.02 - - -0.34* 0.02 - -
     HDL-cholesterol (mg/dL ) 0.08* ns - - 0.07* ns - - 0.04* ns - - 0.11* ns - -
Characteristics of HIV infection
      Nadir CD4+ < 200 (cells/μL) -0.22° 0.03 - - -0.17° ns - - -0.28° 0.01 - - -0.17° ns - -
      Time since HIV  diagnosis -0.20* 0.03 - - -0.14* ns - - -0.14* ns - - -0.05* ns - -
      Score of PI exposure -0.2° 0.02 -0.33 0.02 -0.25° 0.05 - - -0.25° 0.01 -0.5 0.0001 -0.4° 0.02 -0.32 0.02
HIV: Human Immunodeficiency Virus; HCV: Hepatitis C Virus; DXA: Dual-Energy X-Ray Absorptiometry; BMI: Body Mass Index; Ns: Not Significant; HDL: High-Density Lipoprotein; PI: Protease Inhibitor. *R: Pearson’s Correlation Test; °Spearman’s Rank Correlation Test.
Table 5: Correlation between lumbar spine, femoral neck DXA T-scores and the study parameters.
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