Lumbarspine (n=145) Total hip (n=193) At least one site (n=145)
  OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
Female 15.9 (4.2-60.1) <0.001 6.9 (1.2-40.7) 0.03 10.3 (3.3-32.6) <0.001
Age (per 10 years) 1.3 (0.6-3.0) 0.49 1.9 (0.6-5.9) 0.25 1.3 (0.6-2.7) 0.51
BMI (per kg/m2 increase) 0.8 (0.7-1.0) 0.021 0.8 (0.6-1.0) 0.028 0.8 (0.7-1.0) 0.017
Current TDF use 1.8 (0.5-5.9) 0.36 _a _ 1.4 (0.4-4.3) 0.56
Current PI use 1.09 (0.3-4.3) 0.90 _ _ _ _
CD4 cell count<350 cells/μL 3.0 (1.0-8.9) 0.045 _ _ 2.7 (1.0-7.5) 0.048
OR: Odds Ratio; CI: Confidence Interval; BMI: Body Mass Index; ART: Antiretroviral Treatment; TDF: Tenofovir Disoproxyl Fumarate; PI: Protease Inhibitor
aFactors were not included in multivariate models (p-value>0.25 in univariate analysis; see Methods Section).
Table 3: Factors associated with osteoporosis (T-score ≤ -2.5) at lumbar spine, total hip and at least one anatomical site.
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