Drugs included in the modelling of alternative regimens Number (%) of actual failures for which the models identified alternative regimens predicted to be ffective Number (%) of actual failures for which the models identified alternative regimens with a higher probability of success
18 drugs (no tipranavir or maraviroc) 267 (75%) 357 (100%)
13 drugs (no tipranavir, maraviroc, lopinavir, atazanavir, darunavirraltegravir, enfuvirtided: drugs approved in last 10 years) 146 (41%) 351 (98%)
Only those drugs available at the time of the TCE included 143 (40%) 356 (100%)
Table 3: Using the models to identify effective alternatives to regimens that failed.
Goto home»