Figure 1: Airway Remodeling.
The schematic above is split figure with normal airway represented on the left and a remodeled asthmatic airway on the right. The key features of the remodeled airway include mucous cell hyperplasia, thickening of the basement membrane with associated proliferation of myofibroblast, increased vascular density and increased smooth muscle hypertrophy. Together these changes predispose to airway hyper-responsiveness.