Figure 2: NF-κB is required for allergic airway inflammation and AHR. WT and CC10-IκBsr mice were exposed to Ova sensitization and challenge (O/O) or challenge only (A/O) (n = 6, 5 respectively for FlexiVent, n = 8, 5 respectively for cell data), and were analyzed 48 hr after cessation of 6 Ova challenges. Top panels, AHR measured by FlexiVent, Rn - airway resistance, H - tissue elastance. Lower panel, inflammatory cells in BAL fluid. * p < 0.05 versus WT A/O, ** p < 0.05 versus WT O/O.