Figure 4: Antigen sensitization promotes AHR and allergic airway inflammation. WT mice were sensitized to Asp (Asp+Sens) or vehicle (Asp) followed by Asp challenge (n = 4, 3 respectively, 5 for naïve). Top panels, AHR measured by FlexiVent, Rn - airway resistance, H - tissue elastance. Lower panel, inflammatory cells in BAL fluid. * p < 0.05 versus Asp.