Variables |
Patients without diastolic dysfunction
(n = 30) |
Patients with diastolic dysfunction
(n = 31) |
P value |
All hypertensive patients
(n = 61) |
Controls
(n = 21) |
P value |
Age (yr) |
65 ± 10 |
66 ± 8 |
0.74 |
66 ± 9 |
58 ± 12 |
0.003 |
Sex male (n; %) |
28 (93) |
30 (97) |
0.53 |
58 (95) |
18 (86) |
0.18 |
Body mass index (kg.m-2) |
26.5 ± 3.6 |
26.3 ± 3.7 |
0.84 |
26.4 ± 3.6 |
24.4 ± 3.2 |
0.03 |
ASA score (n, %)
- class 1
-class 2
- class 3 |
-
25 (83)
5 (17) |
-
28 (90)
3 (10) |
0.47 |
-
53 (87)
8 (13) |
11 (52)
10 (48)
0 |
0.0001 |
Diabetes (n, %) |
8 (27) |
10 (32) |
0.78 |
18 (29) |
4 (19) |
0.34 |
Preoperative pulse pressure (mmHg) |
67 ± 14 |
63 ± 13 |
0.31 |
65 ± 13 |
53 ± 13 |
0.03 |
Preoperative pulse pressure > 60 mmHg
(n, %) |
21 (70) |
17 (55) |
0.22 |
38 (63) |
6 (29) |
0.008 |
Surgical procedures (n, %)
- radical prostatectomy
- transurethtral procedures
- laparoscopic lymph node removal
- miscellaneous |
14 (47)
6 (20)
4 (13)
6 (20) |
16 (52)
6 (19)
7 (23)
2 (6) |
0.40 |
30 (49)
12 (20)
11 (18)
8 (13) |
10 (48)
3 (14)
1 (5)
7 (33) |
0.37 |
General anesthesia
- propofol (induction; mg.kg-1)
- sufentanil (induction; µg.kg-1)
- cisatracurium (n, %)
- minimum alveolar concentration
of sevoflurane (%)
- sufentanil (total dose, µg.kg-1) |
2.4 ± 0.62
0.24 ± 0.06
19 (63)
1.2 ± 0.93
0.66 ± 0.44 |
2.8 ± 1.2
0.23 ± 0.08
23 (74)
1.2 ± .37
0.57 ± 0.33 |
0.15
0.51
0.36
0.81
0.37 |
2.6 ± 1.0
0.23 ± 0.07
23 (74)
1.2 ± 0.7
0.60 ± 0.4 |
3.0 ± 0.7
0.25 ± 0.07
14 (67)
1.3 ± 0.9
0.59 ± 0.3 |
0.07
0.35
0.99
0.48
0.83 |
Ephedrine (total dose, mg) |
6 [0 – 15] |
6 [0 – 9] |
0.69 |
6 [0 – 12] |
6 [0 – 9] |
0.27 |
Estimated blood loss (ml) |
200 [0 -713] |
200 [0 – 500] |
0.98 |
200 [0 – 500] |
325 [0 – 425] |
0.97 |
Intraoperative volume replacement (ml) |
1500 [1000 – 2000] |
1500 [812 – 2000] |
0.65 |
1500 [1000 – 2000] |
2000 [950 – 2125] |
0.54 |
Median anesthesia time (min) |
190 [115 – 220] |
165 [109 – 218] |
0.56 |
175 [112 – 220] |
185 [112 – 240] |
0.74 |