Variables Patients without diastolic dysfunction (n = 30) Patients with diastolic dysfunction (n = 31) P value All hypertensive patients (n = 61) Controls (n = 21) P value
Age (yr) 65 ± 10 66 ± 8 0.74 66 ± 9 58 ± 12 0.003
Sex male (n; %) 28 (93) 30 (97) 0.53 58 (95) 18 (86) 0.18
Body mass index (kg.m-2) 26.5 ± 3.6 26.3 ± 3.7 0.84 26.4 ± 3.6 24.4 ± 3.2 0.03
ASA score (n, %)
- class 1
-class 2
- class 3
  -
25 (83)
5 (17)
  -
28 (90)
3 (10)
0.47   -
53 (87)
8 (13)
11 (52)
10 (48)
0
0.0001
Diabetes (n, %) 8 (27) 10 (32) 0.78 18 (29) 4 (19) 0.34
Preoperative pulse pressure (mmHg) 67 ± 14 63 ± 13 0.31 65 ± 13 53 ± 13 0.03
Preoperative pulse pressure > 60 mmHg
(n, %)
21 (70) 17 (55) 0.22 38 (63) 6 (29) 0.008
Surgical procedures (n, %)
- radical prostatectomy
- transurethtral procedures
- laparoscopic lymph node removal
- miscellaneous
14 (47)
6 (20)
4 (13)
6 (20)
16 (52)
6 (19)
7 (23)
2 (6)
0.40 30 (49)
12 (20)
11 (18)
8 (13)
10 (48)
3 (14)
1 (5)
7 (33)
0.37
General anesthesia
- propofol (induction; mg.kg-1)
- sufentanil (induction; µg.kg-1)
- cisatracurium (n, %)
- minimum alveolar concentration
of sevoflurane (%)
- sufentanil (total dose, µg.kg-1)

2.4 ± 0.62
0.24 ± 0.06
19 (63)
1.2 ± 0.93

0.66 ± 0.44

2.8 ± 1.2
0.23 ± 0.08
23 (74)
1.2 ± .37

0.57 ± 0.33

0.15
0.51
0.36
0.81

0.37

2.6 ± 1.0
0.23 ± 0.07
23 (74)
1.2 ± 0.7

0.60 ± 0.4

3.0 ± 0.7
0.25 ± 0.07
14 (67)
1.3 ± 0.9

0.59 ± 0.3

0.07
0.35
0.99
0.48

0.83
Ephedrine (total dose, mg) 6 [0 – 15] 6 [0 – 9] 0.69 6 [0 – 12] 6 [0 – 9] 0.27
Estimated blood loss (ml) 200 [0 -713] 200 [0 – 500] 0.98 200 [0 – 500] 325 [0 – 425] 0.97
Intraoperative volume replacement (ml) 1500 [1000 – 2000] 1500 [812 – 2000] 0.65 1500 [1000 – 2000] 2000 [950 – 2125] 0.54
Median anesthesia time (min) 190 [115 – 220] 165 [109 – 218] 0.56 175 [112 – 220] 185 [112 – 240] 0.74
Table 1: Characteristics of hypertensive patients and controls.