Nitric oxide levels (mmol/L) Malondyaldehid levels (nmol/mL) baseline value after painful stimulation baseline value after painful stimulation Group C 23.5±5.4 24.2 ±6.5 0.42±0.07 0.54±0.03 Group ISO 22.4±5.2 23.1±5.9 0.43±0.1 0.56±0.02 Group N 24.2±6.4 93.3±12.4 ▲ 0.42±0.05 0.33±0.09◆ Group L 22.3±5.6 22.5±8.4 0.41±0.05 0.43±0.05 Group L+N 23.4±5.3 39.5±7.3 0.40±0.03 0.32±0.01■ Groups are presented as Group C (no drug was given), Group ISO (isotonic group), Group N (nitroglycerin group; 1 mg kg-1), Group L (lornoxicam group; 1.3 mg kg-1), Group L+N (nitroglycerin-lornoxicam combination group; 1.3 mg kgg-1 lornoxicam+ 1 mg kgg-1 nitroglicerin). ▲In Group N, after painful stimulation compared to baseline values (p<0.001), for nitric oxide levels. ◆In Group N (after painful stimulation) compared to Group C (p= 0.033), Group ISO (p= 0.036), for malondyaldehid levels. ■In Group L+N (after painful stimulation) compared to Group C (p= 0.031), Group ISO (p= 0.028), for malondyaldehid levels.

Table 2: Changes in nitric oxide and malondialdehyde levels before drugs administration and after painful stimulation.