Glutathione (mmol/g Hb)
Catalase (k/g Hb)
baseline value
after painful stimulation
baseline value
after painful stimulation
Group C

3.32±0.47

3.29 ±0.41

418.43±51.24

406.38±44.23

Group ISO

3.25±0.56

3.34±0.36

420.32±63.91

412.44 ±58.82

Group N

3.29±0.34

4.71±0.44 ▲

416.74±48.63

589.38±54.83★

Group L

3.43±0.38

3.82±0.42■

420.26±87.18

492.42 ±39.45•

Group L+N

3.33±0.45

5.52±0.24◆

421.34±75.96

687.36 ±62.75✯

Data are means ± SD
▲After painful stimulation, in Group N, compared to Group C (p=0.0022), Group
ISO (p=0.0028) and Group L (p=0.032) for glutathione levels.
■After painful stimulation, in Group L+N, compared to Group C (p<0.0001), Group
ISO (p<0.0001), Group L (p<0.0001) and Group N (p=0.041) in for glutathione
levels.
◆After painful stimulation, in Group L, compared to Group C (p=0.043), Group
ISO (p=0.042), for glutathione levels.
★After painful stimulation, in Group N, compared to Group C (p=0.0024), Group
ISO (p=0.0019) and Group L (p=0.028) for catalase levels.
•After painful stimulation, in Group L+N, compared to Group C (p<0.0001), Group
ISO (p<0.0001) and Group L (p=0.005) for catalase levels.
✯After painful stimulation, in Group L, compared to Group C (p=0.024) and Group
ISO (p=0.022) for catalase levels.
Table 3: Changes in glutathione and catalase levels before drugs administration and after painful stimulation.