Variable

Normal Physiology

Cardiac Transplant

One Ventricle Physiology

Baseline

Cardiac Output

4±1.8

5.4±1.5

4.2±2.8

Cardiac Index

5.6±0.9

5±1.5

4.8±1.7

SVR

10.4±2.2

12.3±4.2

10.8±3.2

PVR

1.2±0.6

1.2±0.6

1.3±0.7

Mean PAP

20±4

20±5

11±3

Steady-state (sevoflurane+dexmedetomidine)

Cardiac Output

3.4±1.8

4.6±2.9

2.9±1.9

Cardiac Index

5±1

3.8±1.4

3.3±1

SVR

12.9±2.4

18.1±7

18.2±5.6

PVR

0.9±0.4

1.3±0.7

1.2±0.7

Mean PAP

19±4

18.8±4.5

14±3

*SVR indicates systemic vascular resistance; PVR pulmonary vascular resistance; PAP pulmonary artery pressure