Left shift (>affinity for O2) Right shift (<affinity for O2)
Temperature Decrease Increase
2,3-diphosphoglycerate(2.3-GPD) Decrease Increase
p(CO2) Decrease Increase
p(CO) Increase Decrease
pH (Bohr effect) Increase (alkalosis) Decrease (acidosis)
Type of hemoglobin Fetal hemoglobin Adult hemoglobin
Table 1: Factors that affect the oxygen-hemoglobin dissociation curve.