|
Group |
T1 |
T2 |
T3 |
T4 |
T5 |
|
INR |
C |
1.85 ± 0.40 |
2.10 ± 0.45* |
1.91 ± 0.22 |
2.14 ± 0.30* |
2.40 ± 0.27* |
| R |
1.89 ± 0.43 |
1.13 ± 0.13*# |
1.27 ± 0.17*# |
2.29 ± 0.49* |
2.56 ± 0.31* |
APTT
SEC |
C |
60.90 ± 17 |
66.84 ± 14.24 |
77.52 ± 15.7** |
90.5 ± 9.9** |
92.48 ± 12.30** |
| R |
58.80 ± 12.57 |
42.54 ± 9.55**# |
58.94 ± 8.69# |
96.6 ± 14.8** |
92.04 ± 7.56** |
|
Platelets/mm3 |
C |
58.8 ± 25.9 |
63.7 ± 24.43 |
63 ± 13.42 |
49.1 ± 13.9 |
47.56 ± 9.97 |
| R |
62.64 ± 27 |
64.68 ± 26 |
61.76 ± 19.60 |
50.08 ± 15.19 |
50.52 ± 73.13 |
|
Fibrinogen
(mg/dl) |
C
R |
126 ± 37.3 |
120.6 ± 24.63 |
93 ± 24.65* |
66.7 ± 16.7* |
58.8 ± 11.68* |
| |
130 ± 75.2 |
98.8 ± 48*# |
89.6 ± 50.7* |
55.6 ± 18.*# |
49.8 ± 16.34*# |
C, Control group R, rFVIIa group INR, International Normalization Ratio T1, preoperative T2, half an hour after the first dose T3, half an hour after the second dose
T4, after reperfusion T5, at the end of surgery. * P<0.05 relative to the preoperative value of the same group is considered statistically significant. # P<0.05 relative to the
similar value of C group is considered statistically significant |
