| Parameter |
Control |
Lidocaine |
Diltiazem |
Esmolol |
p-value |
| SBP (mmHg) |
153.1 ± 2.025 |
140.7 ± 1.575 *** |
137.6 ± 1.37*** |
137.5 ± 1.40*** |
P<0.0001 |
| DBP (mmHg) |
99.38 ± 0.82 |
98.50 ± 0.77 |
91.93 ± 0.81*** |
90.43 ± 0.93*** |
P<0.0001 |
| HR (per min) |
116.1 ± 1.20 |
110.0 ± 0.78*** |
92.88 ± 0.99*** |
92.20 ± 1.54*** |
P<0.0001 |
| MAP (mmHg) |
117.3 ± 0.94 |
112.6 ± 0.70*** |
107.1 ± 0.77*** |
106.1 ± 0.79*** |
P<0.0001 |
| RPP |
17780 ± 304.5 |
15460 ± 170.1 *** |
12770 ± 182.4 *** |
12680 ± 253.7 *** |
P<0.0001 |
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. p is
significant at < 0.05*, < 0.01** and <0.001*** |
