Parameter |
Control |
Lidocaine |
Diltiazem |
Esmolol |
p-value |
SBP (mmHg) |
131.6 ± 1.59 |
131.2 ± 1.79 |
128.2 ± 1.45 |
126.3 ± 1.37 |
0.0478 |
DBP (mmHg) |
87.10 ± 0.87 |
86.00 ± 0.88 |
83.50 ± 0.73* |
79.03 ± 0.93*** |
P<0.0001 |
HR (per min) |
98.13 ± 1.47 |
97.80 ± 1.40 |
87.70 ± 1.41** |
88.20 ± 1.39*** |
P<0.0001 |
MAP (mmHg) |
101.9 ± 0.75 |
101.1 ± 0.76 |
98.38 ± 0.73** |
94.77 ± 0.77*** |
P<0.0001 |
RPP |
12910 ± 248.8 |
12840 ± 261.7 |
11270 ± 257.9 *** |
11140 ± 221.5*** |
P<0.0001 |
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. p is
significant at <0.05*, <0.01** and <0.001*** |