Parameter Lidocaine Diltiazem Esmolol PI PII PIII PIV
SBP (mmHg) 140.7 ± 1.575 137.6 ± 1.37 137.5 ± 1.40 0.2068 0.1381 0.1301 0.9594
DBP (mmHg) 98.50 ± 0.77 91.93 ± 0.81 90.43 ± 0.93 P<0.0001 P<0.0001 P<0.0001 0.2277
HR (per min) 110.0 ± 0.78 92.88 ± 0.99 92.20 ± 1.54 P<0.0001 P<0.0001 P<0.0001 0.7131
MAP (mmHg) 112.6 ± 0.70 107.1 ± 0.77 106.1 ± 0.79 P<0.0001 P<0.0001 P<0.0001 0.3493
RPP 15460 ± 170.1 12770 ± 182.4 12680 ± 253.7 P<0.0001 P<0.0001 P<0.0001 0.7690
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. Bonferroni’s multiple comparison tests were used to make intragroup comparisons. Comparison PI-L,D&E, PII-L&D, PIII-L&E, PIV-D&E
Table 6: Change in haemodynamic variables in the study groups at 1 min with intragroup comparison.