Parameter |
Lidocaine |
Diltiazem |
Esmolol |
PI |
PII |
PIII |
PIV |
SBP (mmHg) |
140.7 ± 1.575 |
137.6 ± 1.37 |
137.5 ± 1.40 |
0.2068 |
0.1381 |
0.1301 |
0.9594 |
DBP (mmHg) |
98.50 ± 0.77 |
91.93 ± 0.81 |
90.43 ± 0.93 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.2277 |
HR (per min) |
110.0 ± 0.78 |
92.88 ± 0.99 |
92.20 ± 1.54 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.7131 |
MAP (mmHg) |
112.6 ± 0.70 |
107.1 ± 0.77 |
106.1 ± 0.79 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.3493 |
RPP |
15460 ± 170.1 |
12770 ± 182.4 |
12680 ± 253.7 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.7690 |
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. Bonferroni’s
multiple comparison tests were used to make intragroup comparisons. Comparison PI-L,D&E, PII-L&D, PIII-L&E, PIV-D&E |