Parameter Lidocaine Diltiazem Esmolol PI PII PIII PIV
SBP (mmHg) 136.7 ± 1.29 133.1 ± 1.29 131.9 ± 1.39 0.0293 0.0487 0.0125 0.5291
DBP (mmHg) 91.80 ± 0.88 85.15 ± 0.85 82.63 ± 0.83 P<0.0001 P<0.0001 P<0.0001 0.0367
HR (per min) 101.1 ± 1.31 89.90 ± 1.08 91.40 ± 1.19 P<0.0001 P<0.0001 P<0.0001 0.3529
MAP (mmHg) 106.8 ± 0.70 101.1 ± 0.80 99.04 ± 0.65 P<0.0001 P<0.0001 P<0.0001 0.0473
RPP 13810 ± 200.5 11980 ± 205.2 12060 ± 213.7 P<0.0001 P<0.0001 P<0.0001 0.7704
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. Bonferroni’s multiple comparison tests were used to make intragroup comparisons. Comparison PI-L, D&E, PII-L&D, PIII-L&E, PIV-D&E
Table 7: Change in haemodynamic variables in the study groups at 3 min with intragroup comparison.