Parameter |
Lidocaine |
Diltiazem |
Esmolol |
PI |
PII |
PIII |
PIV |
SBP (mmHg) |
136.7 ± 1.29 |
133.1 ± 1.29 |
131.9 ± 1.39 |
0.0293 |
0.0487 |
0.0125 |
0.5291 |
DBP (mmHg) |
91.80 ± 0.88 |
85.15 ± 0.85 |
82.63 ± 0.83 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.0367 |
HR (per min) |
101.1 ± 1.31 |
89.90 ± 1.08 |
91.40 ± 1.19 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.3529 |
MAP (mmHg) |
106.8 ± 0.70 |
101.1 ± 0.80 |
99.04 ± 0.65 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.0473 |
RPP |
13810 ± 200.5 |
11980 ± 205.2 |
12060 ± 213.7 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.7704 |
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values.
Bonferroni’s multiple comparison tests were used to make intragroup comparisons. Comparison PI-L, D&E, PII-L&D, PIII-L&E, PIV-D&E |