Parameter |
Lidocaine |
Diltiazem |
Esmolol |
PI |
PII |
PIII |
PIV |
SBP (mmHg) |
131.2 ± 1.79 |
128.2 ± 1.45 |
126.3 ± 1.37 |
0.0758 |
0.1853 |
0.0302 |
0.3428 |
DBP (mmHg) |
86.00 ± 0.88 |
83.50 ± 0.73 |
79.03 ± 0.93 |
P<0.0001 |
0.0318 |
P<0.0001 |
0.0003 |
HR (per min) |
97.80 ± 1.40 |
87.70 ± 1.41 |
88.20 ± 1.39 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.8013 |
MAP (mmHg) |
101.1 ± 0.76 |
98.38 ± 0.73 |
94.77 ± 0.77 |
P<0.0001 |
0.0124 |
P<0.0001 |
0.001 |
RPP |
12840 ± 261.7 |
11270 ± 257.9 |
11140 ± 221.5 |
P<0.0001 |
P<0.0001 |
P<0.0001 |
0.713 |
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. Bonferroni’s
multiple comparison tests were used to make intragroup comparisons. Comparison PI-L, D&E, PII-L&D, PIII-L&E, PIV-D&E |