| |
Tranexamic Acid
N = 70 |
No Tranexamic Acid
N = 160 |
P Value |
Following surgery to POD 4
# Patients receiving PRBC (%) |
11 (16%) |
63 (39%) |
< 0.001 |
Operating Room:
# Patients receiving PRBC (%) |
14 (20%) |
51 (32%) |
0.09 |
Operating Room:
PRBC Volume ml |
292 (250, 345)
N = 14 |
450 (295, 559)
N=51 |
< 0.01 |
Operating Room:
Estimated Blood Loss ml |
437 (300, 700) |
550 (400, 800) |
0.01 |
| First Hematocrit after surgery |
30.6 (29.0, 33.5) |
30.7 (28.5, 32.8) |
0.78 |
| Hematocrit POD 1 |
28.7 (27.1, 30.6)
N = 64 |
26.2 (24.1, 28.6)
N = 156 |
< 0.001 |
| Hematocrit POD 2 |
27.5 (25.3, 30.1)
N = 60 |
27.1 (24.6, 29.6)
N = 139 |
0.21 |
| Hematocrit POD 3 |
27.4 (24.8, 29.9)
N = 50 |
26.4 (24.4, 29.3)
N = 121 |
0.26 |
| Hematocrit POD 4 |
27.6 (24.2, 29.6)
N = 39 |
26.6 (24.8, 29.0)
N = 91 |
0.29 |
Lowest Hematocrit in group
not receiving PRBC transfusion |
27.8 (25.5, 30.2)
N = 50 |
25.6 (24.0, 27.7)
N = 71 |
< 0.01 |
Hematocrit prior to PRBC
transfusion
in the operating room |
25.5 (25.0, 30.0)
N = 14 |
25.0 (23.0, 27.0)
N = 51 |
0.14 |
Hematocrit prior to PRBC
transfusion
following surgery to POD 4 |
24.2 (22.6, 24.9)
N = 11 |
23.2 (21.7, 25.3)
N = 58 |
0.57 |
| Sub-group: Patients receiving PRBC
following surgery to POD 4 |
| All patients received: |
|
|
|
| Intrathecal opioid medication |
10 (17%)
N = 60 |
56 (39%)
N = 142 |
< 0.01 |
| TIVA |
11 (16%)
N = 68 |
36 (36%)
N = 99 |
< 0.01 |
Intrathecal opioid medications
and TIVA |
10 (17%)
N = 59 |
34 (38%)
N = 89 |
< 0.01 |
|
