CRPS type 1 NocP subgroup NeP subgroup Pvalue N 36 17 19 - Age (years) 48.1 ± 16.9 51.9 ± 15.2 44.7 ± 18.0 0.21 Gender (female) 22 9 13 <0.01 Pain duration (month) 441.0 ± 234.0 378.9 ± 248.3 496.6 ± 211.4 0.72 NRS (pain intensity) 6.4 ± 1.8 6.2 ± 1.6 6.5 ± 2.8 0.64 MPQ total score 21.5 ± 14.2 22.9 ± 14.8 20.2 ± 13.9 0.58 HAD score Anxiety 8.6 ± 4.1 8.0 ± 4.2 9.2 ± 4.2 0.43 HAD score Depression 9.6 ± 5.8 11.3 ± 7.0 8.2 ± 4.2 0.15 PDAS score 26.0 ± 14.3 27.9 ± 15.1 24.4 ± 13.9 0.50

Table 2: Demographic data of 36 CRPS type 1 patients, 19 neuropathic pain and 17 nociceptive pain subgroups. CRPS type 1 patients were divided into neuropathic pain and nociceptive pain subgroups on the basis of the discriminant function which is obtained in Experiment 1. Numerical values indicate means ± SD. Statistical analyses were performed using the Mann-Whitney test.NocP indicates nociceptive pain; NeP indicates neuropathic pain; NRS indicates numerical rating scale of pain intensity.