•Cirrhosis and ascites
•Serum creatinine> 1.5 mg/dL
•No improvement of serum creatinine (decrease to a level of <= 1.5 mg/dL) after at least 2 days with diuretic withdrawal and volume expansion with albumin
•No signs of shock
•No recent use of nephrotoxic drugs
•Absence of parenchymal kidney disease as indicated by proteinuria >500 mg/day, microhematuria (>50 red blood cells per high power field) and/or abnormal renal ultrasonography
*Criteria have been developed by the International Ascites Club. Modified from [Gut, Salerno, F. et al. 56, 1310-1318, C 2007]
Table 1: New diagnostic criteria for hepatorenal syndrome*.