Without TXA With TXA
Number (n) 25 81
Gender (proportion of female %) 60 57
Age (years) 73 ± 10 67 ± 12
Comorbidities    
Body mass index (kg/m2) 26 ± 4 27 ± 5
Median ASA score (Q1;Q3) 3 (3;3) 2 (2;2)
Cardio-vascular history (%) 80 14
Antiplatelet agents at D-30 (%) 44 20
Anticoagulant agents D-30 (%) 28 2
Hb D-1 (g/dL) 13.3 ± 1.1 13.4 ± 1.1
Type of surgery    
THR (%) 60 50
TKR (%) 32 29
RTHR (%) 8 21
Perioperative period    
Tranexamic acid    
Intraoperative dose (mg/kg) 0 17 ± 15
Dose per 24h (mg/kg/24h) 0 75 ± 25
Fluids (intraoperative and RR, in mL) 2140 ± 700 2080 ± 764
Postoperative intravenous iron (%) 80 87
Transfusion    
Allogeneic transfusion (between D0 et D+5, in %) 40 11
Number of transfused patients (n) 10 9
THR (%) 40 5
TKR (%) 25 5
RTHR (%) 100 38
Median number of RBC unit (Q1,Q3) 2 (2;3) 2 (2;2)
Mean Hb transfusional threshold (g/dL) 8.4 ± 1,3 9.1 ± 0,6
TXA: Tranexamic Acid; ASA: American Society of Anesthesiology; Hb: Hemoglobin; THR: Total Hip Replacement; TKR: Total Knee Replacement; RTHR: Revision Total Hip Replacement; RBC: Red Blood Cell
Table 2: Patient characteristics broken down by TXA vs. no TXA administration