Variable Serum Lidocaine Coefficient Corcelation ( r ) Significancy (p) HR r= - 0.701 p=0.000 SBP r= - 0.823 p=0.000 DBP r= - 0.788 p=0.000 IL-6 serum Concentration r= - 0.677 p=0.000 PLA2 serum Concentration r= - 0.734 p=0.000

Table 5: The correlation between lidocaine concentration with IL-6 and PLA2 serum concentration, HR, SBP and DBP after giving 2 hours infusion.