Clinical Interest |
Time Indicator |
Propofol (mcg/ml) |
Remifentnail
(ng/ml) |
Fentanyl
(ng/ml) |
Laryngoscopy |
L |
7.2 (1.5) |
1.1 (0.4) |
2.8 (0.9) |
Skin Incision |
S |
2.7 (0.4) |
5.3 (1.0) |
1.2 (0.3) |
Emergence |
E |
1.6 (0.4) |
2.8 (0.9) |
1.9 (0.7) |
PACU |
P |
0.6 (0.1) |
0.3 (0.3) |
1.0 (0.4) |
The drug effect site concentration mean (standard deviation) at clinical points of
interest for simulated dosing scheme as described in the methods. The clinical
points of interest are the times for induction, skin incision, re-emergence, and postanesthesia
care unit (PACU) arrival. The time indicators for each of the clinical
interest points are shown in figure 1. |