| |
Propofol (mcg/kg/min) |
| 80 |
100 |
120 |
| Fentanyl
(mcg/kg) |
1 |
10 (4) |
11 (4) |
12 (4) |
| 2 |
12 (5) |
13 (5) |
15 (5) |
| 3 |
15 (6) |
16 (6) |
17 (7) |
Data are presented as the mean (standard deviation) time (in minutes) from
termination of the propofol and remifentanil infusions to 50% intolerable ventilator
depression (IVD) for each dosing scheme. The remifentanil infusion was held
constant at 0.2 mcg/kg/min. A difference of 3 minutes was considered to be of
clinical significance. |
