Age |
|
Mean (range) |
15.6 years (7.5-21.4) |
Gender |
|
Female |
22(67%) |
Phenotype |
|
SS |
23 (70%) |
SBeta0Thalassemia |
1 (3%) |
SC |
8 (24%) |
SBeta+ Thalassemia |
1 (3%) |
Co-morbidities |
|
Asthma or hx of severe ACS |
23 (70%) |
Avascular Necrosis |
5 (15%) |
Iron overload |
3 (9%) |
Kidney Disease/HTN |
6 (18%) |
Priapism |
1 (3%) |
Hydroxyurea therapy |
|
Yes |
12 (42%) |
Average dose |
22.74 mg/kg/day |
Time to Ketamine start (±SD (range) |
1.17 days (±0.99) (0.09 – 3.56) |
PCA type |
Morphine 21 (64%) |
Hydromorphone 12 (36%) |
|
Day Ketamine Added |
HD 1 (n = 6) |
|
HD 2 (n = 13) |
|
HD 3 (n = 7) |
|
HD 4 (n = 6) |
|
HD 5 (n = 1) |
Total Duration of Ketamine (±SD) 3.11 days (±2.29) |
hx=history ACS=Acute Chest Syndrome, HTN=Hypertension, HD=hospital day |