| Summary of the metabolomics analysis for the asphyxia condition |
| Approach (Un targeted/Targeted) |
Analytical techniques |
Animal/Human sampling |
Biofluid |
Key metabolic pathways |
Reference |
| Targeted |
Spectrophotometry
HPLC |
Human (Newborns) |
Blood |
Production of oxidative stress biomarkers, and significantly higher value of cTnT and NAG . |
Vento et al. [20] |
| Targeted |
ESI MS/MS
LC-MS/MS |
Animal
(Piglets) |
Plasma |
The metabolites key components of Krebs cycle metabolism, glycine and amino acid metabolisms. |
Solberg et al. [21] |
| Untargeted |
NMR/MVA |
Animal
(Piglets) |
Urine |
Resuscitation with lower oxygen concentration was associated with cellular homeostasis, maintenance, and carbohydrates metabolisms.
Higher oxygen concentration was characterized by ROS production. |
Fanos et al. [22] |
